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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Histone deacetylase 2

SKU : BHE13805162

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15286h
Categories	Elisa
Function	Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.
Specificity	Natural and recombinant Human Histone deacetylase 2
Subcellular Location	Nucleus
Entryname	HDAC2_HUMAN
Platform	PF00850
Protein Name	Histone deacetylase 2
Sequence	50: MAYSQGGGKK ; KVCYYYDGDI ; GNYYYGQGHP ; MKPHRIRMTH ; NLLLNYGLYR ; 100: KMEIYRPHKA ; TAEEMTKYHS ; DEYIKFLRSI ; RPDNMSEYSK ; QMQRFNVGED ; 150: CPVFDGLFEF ; CQLSTGGSVA ; GAVKLNRQQT ; DMAVNWAGGL ; HHAKKSEASG ; 200: FCYVNDIVLA ; ILELLKYHQR ; VLYIDIDIHH ; GDGVEEAFYT ; TDRVMTVSFH ; 250: KYGEYFPGTG ; DLRDIGAGKG ; KYYAVNFPMR ; DGIDDESYGQ ; IFKPIISKVM ; 300: EMYQPSAVVL ; QCGADSLSGD ; RLGCFNLTVK ; GHAKCVEVVK ; TFNLPLLMLG ; 350: GGGYTIRNVA ; RCWTYETAVA ; LDCEIPNELP ; YNDYFEYFGP ; DFKLHISPSN ; 400: MTNQNTPEYM ; EKIKQRLFEN ; LRMLPHAPGV ; QMQAIPEDAV ; HEDSGDEDGE ; 450: DPDKRISIRA ; SDKRIACDEE ; FSDSEDEGEG ; GRRNVADHKK ; GAKKARIEED ; 488: KKETEDKKTD ; VKEEDKSKDN ; SGEKTDTKGT ; KSEQLSNP
Sequence Length	488
String	Q92769
Sub Unit	Interacts with the non-histone region of H2AFY (By similarity). Part of the core histone deacetylase (HDAC) complex composed of HDAC1, HDAC2, RBBP4 and RBBP7. The core complex associates with MTA2, MBD3, MTA1L1, CHD3 and CHD4 to form the nucleosome remodeling and histone deacetylation (NuRD) complex, or with SIN3, SAP18 and SAP30 to form the SIN3 HDAC complex. Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Part of a complex containing the core histones H2A, H2B, H3 and H4, DEK and unphosphorylated DAXX. Part of a complex containing ATR and CHD4. Forms a heterologous complex at least with YY1. Interacts with ATR, DNMT1, MINT, HDAC7, HDAC10, HCFC1, NRIP1, MJD2A/JHDM3A, PRDM6, SAP30, SETDB1 and SUV39H1. Interacts with the non-histone region of H2AFY. Interacts with PELP1. Component of a mSin3A corepressor complex that contains SIN3A, SAP130, SUDS3/SAP45, ARID4B/SAP180, HDAC1 and HDAC2. Interacts with CBFA2T3. Interacts with CHFR and SAP30L. Interacts (CK2 phosphorylated form) with SP3. Interacts with TSHZ3 (via N-terminus); the interaction is direct. Interacts with APEX1; the interaction is not dependent on the acetylated status of APEX1.

Uniprot	Q92769
Gene Name	HDAC2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3066
Unigene	Hs.3352

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805162	E15286h	96T	$736		Add to Cart

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