HERV-K(C7) Gag protein ; HERV-K(HML-2.HOM) Gag protein ; HERV-K108 Gag protein
Categories
Elisa
Function
The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Endogenous Gag proteins may have kept, lost or modified their original function during evolution.
Specificity
Natural and recombinant Human HERV-K_7p22.1 provirus ancestral Gag polyprotein
Subcellular Location
Cell membrane Lipid-anchor Cytoplasmic membrane (in a transfection system).