Adenylate cyclase-stimulating G alpha protein ; Extra large alphas protein ; XLalphas ; GNAS1
Categories
Elisa
Function
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
Specificity
Natural and recombinant Human Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Interacts through its N-terminal region with ALEX which is produced from the same locus in a different open reading frame. This interaction may inhibit its adenylyl cyclase-stimulating activity.