ELISA Kit for Human GTP cyclohydrolase 1

Mfr.No.	E15349h
Alternative Names	GTP cyclohydrolase I ; GTP-CH-I ; DYT5 ; GCH
Categories	Elisa
Function	Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown.
Specificity	Natural and recombinant Human GTP cyclohydrolase 1
Subcellular Location	Cytoplasm Nucleus
Entryname	GCH1_HUMAN
Platform	PF01227
Protein Name	GTP cyclohydrolase 1
Sequence	50: MEKGPVRAPA ; EKPRGARCSN ; GFPERDPPRP ; GPSRPAEKPP ; RPEAKSAQPA ; 100: DGWKGERPRS ; EEDNELNLPN ; LAAAYSSILS ; SLGENPQRQG ; LLKTPWRAAS ; 150: AMQFFTKGYQ ; ETISDVLNDA ; IFDEDHDEMV ; IVKDIDMFSM ; CEHHLVPFVG ; 200: KVHIGYLPNK ; QVLGLSKLAR ; IVEIYSRRLQ ; VQERLTKQIA ; VAITEALRPA ; 250:
Sequence Length	250
String	P30793
Sub Unit	Toroid-shaped homodecamer, composed of a dimer of pentamers. The inactive isoforms also form decamers and may possibly be incorporated into GCH1 heterodecamers, decreasing enzyme stability and activity. Interacts with AHSA1 and GCHFR/GFRP.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804973	E15349h	96T	$736		Add to Cart