Connexin-43 ; Cx43 ; Gap junction 43 kDa heart protein ; GJAL
Categories
Elisa
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.
Specificity
Natural and recombinant Human Gap junction alpha-1 protein
Subcellular Location
Cell membrane Multi-pass membrane protein Cell junction gap junction
A connexon is composed of a hexamer of connexins. Interacts (via C-terminus) with TJP1. Interacts (via C-terminus) with SRC (via SH3 domain) (By similarity). Interacts with SGSM3. Interacts with KIAA1432/CIP150. Interacts with CNST.