ELISA Kit for Human Fibroblast growth factor 19

Mfr.No.	E1421h
Alternative Names	UNQ334/PRO533
Categories	Elisa
Function	Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
Specificity	Natural and recombinant Human Fibroblast growth factor 19
Subcellular Location	Secreted
Detection Range	15.6-1000pg/mL
Entryname	FGF19_HUMAN
Method Type	Sandwich
Platform	PF00167
Protein Name	Fibroblast growth factor 19
Sensitivity	7.8pg/mL
Sequence	50: MRSGCVVVHV ; WILAGLWLAV ; AGRPLAFSDA ; GPHVHYGWGD ; PIRLRHLYTS ; 100: GPHGLSSCFL ; RIRADGVVDC ; ARGQSAHSLL ; EIKAVALRTV ; AIKGVHSVRY ; 150: LCMGADGKMQ ; GLLQYSEEDC ; AFEEEIRPDG ; YNVYRSEKHR ; LPVSLSSAKQ ; 200: RQLYKNRGFL ; PLSHFLPMLP ; MVPEEPEDLR ; GHLESDMFSS ; PLETDSMDPF ; 216: GLVTGLEAVR ; SPSFEK
Sequence Length	216
String	O95750
Sub Unit	Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with KL; this interaction is direct. Interacts with KLB; this interaction is direct. Interacts with FGFR4 in the presence of heparin, KL or KLB.

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13804235	E1421h	96T	-		Add to Quote