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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Fermitin family homolog 1

SKU : BHE13804875

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14765h
Alternative Names	Kindlerin ; Kindlin syndrome protein ; Kindlin-1 ; Unc-112-related protein 1 ; C20orf42 ; KIND1 ; URP1
Categories	Elisa
Function	Involved in cell adhesion. Contributes to integrin activation. When co-expressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.
Specificity	Natural and recombinant Human Fermitin family homolog 1
Subcellular Location	Cytoplasm cytoskeleton Cell junction focal adhesion Cell projection ruffle membrane Peripheral membrane protein Cytoplasmic side Constituent of focal adhesions. Localized at the basal aspect of skin keratinocytes, close to the cell membrane. Colocalizes with filamentous actin. Upon TGFB1 treatment, it localizes to membrane ruffles.
Detection Range	78-5000pg/mL
Entryname	FERM1_HUMAN
Method Type	Sandwich
Platform	PF00373
Protein Name	Fermitin family homolog 1
Sensitivity	39.2pg/mL
Sequence	50: MLSSTDFTFA ; SWELVVRVDH ; PNEEQQKDVT ; LRVSGDLHVG ; GVMLKLVEQI ; 100: NISQDWSDFA ; LWWEQKHCWL ; LKTHWTLDKY ; GVQADAKLLF ; TPQHKMLRLR ; 150: LPNLKMVRLR ; VSFSAVVFKA ; VSDICKILNI ; RRSEELSLLK ; PSGDYFKKKK ; 200: KKDKNNKEPI ; IEDILNLESS ; PTASGSSVSP ; GLYSKTMTPI ; YDPINGTPAS ; 250: STMTWFSDSP ; LTEQNCSILA ; FSQPPQSPEA ; LADMYQPRSL ; VDKAKLNAGW ; 300: LDSSRSLMEQ ; GIQEDEQLLL ; RFKYYSFFDL ; NPKYDAVRIN ; QLYEQARWAI ; 350: LLEEIDCTEE ; EMLIFAALQY ; HISKLSLSAE ; TQDFAGESEV ; DEIEAALSNL ; 400: EVTLEGGKAD ; SLLEDITDIP ; KLADNLKLFR ; PKKLLPKAFK ; QYWFIFKDTS ; 450: IAYFKNKELE ; QGEPLEKLNL ; RGCEVVPDVN ; VAGRKFGIKL ; LIPVADGMNE ; 500: MYLRCDHENQ ; YAQWMAACML ; ASKGKTMADS ; SYQPEVLNIL ; SFLRMKNRNS ; 550: ASQVASSLEN ; MDMNPECFVS ; PRCAKRHKSK ; QLAARILEAH ; QNVAQMPLVE ; 600: AKLRFIQAWQ ; SLPEFGLTYY ; LVRFKGSKKD ; DILGVSYNRL ; IKIDAATGIP ; 650: VTTWRFTNIK ; QWNVNWETRQ ; VVIEFDQNVF ; TAFTCLSADC ; KIVHEYIGGY ; 677: IFLSTRSKDQ ; NETLDEDLFH ; KLTGGQD
Sequence Length	677
String	Q9BQL6
Sub Unit	Interacts with the cytoplasmic domain of integrins ITGB1 and ITGB3.

Uniprot	Q9BQL6
Gene Name	FERMT1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:55612
Unigene	Hs.472054

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804875	E14765h	96T	$736		Add to Cart

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