3-keto acyl-CoA synthase ELOVL1 ; ELOVL fatty acid elongase 1 ; ELOVL FA elongase 1 ; Very long chain 3-ketoacyl-CoA synthase 1 ; Very long chain 3-oxoacyl-CoA synthase 1 ; SSC1 ; CGI-88
Categories
Elisa
Function
Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids. Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis.
Specificity
Natural and recombinant Human Elongation of very long chain fatty acids protein 1
Subcellular Location
Endoplasmic reticulum membrane Multi-pass membrane protein