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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Dynamin-1-like protein

SKU : BHE13803144

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E14496h
Alternative Names	Dnm1p/Vps1p-like protein ; DVLP ; Dynamin family member proline-rich carboxyl-terminal domain less ; Dymple ; Dynamin-like protein ; Dynamin-like protein 4 ; Dynamin-like protein IV ; HdynIV ; Dynamin-related protein 1 ; DLP1 ; DRP1
Categories	Elisa
Function	Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.
Specificity	Natural and recombinant Human Dynamin-1-like protein
Subcellular Location	Cytoplasm cytosol Golgi apparatus Endomembrane system Peripheral membrane protein Mainly cytosolic. Translocated to the mitochondrial membrane through interaction with FIS1. Colocalized with MARCH5 at mitochondrial membrane. Localizes to mitochondria at sites of division. Associated with peroxisomal membranes, partly recruited there by PEX11B. May also be associated with endoplasmic reticulum tubules and cytoplasmic vesicles and found to be perinuclear. In some cell types, localizes to the Golgi complex.
Detection Range	0.78-50ng/ml
Entryname	DNM1L_HUMAN
Method Type	Competitive
Platform	PF01031
Protein Name	Dynamin-1-like protein
Sensitivity	0.41ng/mL
Sequence	50: MEALIPVINK ; LQDVFNTVGA ; DIIQLPQIVV ; VGTQSSGKSS ; VLESLVGRDL ; 100: LPRGTGIVTR ; RPLILQLVHV ; SQEDKRKTTG ; EENGVEAEEW ; GKFLHTKNKL ; 150: YTDFDEIRQE ; IENETERISG ; NNKGVSPEPI ; HLKIFSPNVV ; NLTLVDLPGM ; 200: TKVPVGDQPK ; DIELQIRELI ; LRFISNPNSI ; ILAVTAANTD ; MATSEALKIS ; 250: REVDPDGRRT ; LAVITKLDLM ; DAGTDAMDVL ; MGRVIPVKLG ; IIGVVNRSQL ; 300: DINNKKSVTD ; SIRDEYAFLQ ; KKYPSLANRN ; GTKYLARTLN ; RLLMHHIRDC ; 350: LPELKTRINV ; LAAQYQSLLN ; SYGEPVDDKS ; ATLLQLITKF ; ATEYCNTIEG ; 400: TAKYIETSEL ; CGGARICYIF ; HETFGRTLES ; VDPLGGLNTI ; DILTAIRNAT ; 450: GPRPALFVPE ; VSFELLVKRQ ; IKRLEEPSLR ; CVELVHEEMQ ; RIIQHCSNYS ; 500: TQELLRFPKL ; HDAIVEVVTC ; LLRKRLPVTN ; EMVHNLVAIE ; LAYINTKHPD ; 550: FADACGLMNN ; NIEEQRRNRL ; ARELPSAVSR ; DKSSKVPSAL ; APASQEPSPA ; 600: ASAEADGKLI ; QDSRRETKNV ; ASGGGGVGDG ; VQEPTTGNWR ; GMLKTSKAEE ; 650: LLAEEKSKPI ; PIMPASPQKG ; HAVNLLDVPV ; PVARKLSARE ; QRDCEVIERL ; 700: IKSYFLIVRK ; NIQDSVPKAV ; MHFLVNHVKD ; TLQSELVGQL ; YKSSLLDDLL ; 736: TESEDMAQRR ; KEAADMLKAL ; QGASQIIAEI ; RETHLW
Sequence Length	736
String	O00429
Sub Unit	Homotetramer; dimerizes through the N-terminal GTP-middle region of one molecule binding to the GED domain of another DNM1L molecule. Can self-assemble in multimeric ring-like structures. Interacts with BCL2L1; the interaction stimulates the GTPase activity of DMN1L in synapses and increases the number of axonal mitochondria and the size and number of synaptic vesicle clusters. Interacts with FIS1 (By similarity). Interacts with GSK3B and MARCH5. Interacts (via the GTPase and B domains) with UBE2I; the interaction promotes sumoylation of DNM1L, mainly in ite B domain. Interacts with PPP3CA; the interaction dephosphorylates DNM1L and regulates its transition to mitochondria. Interacts witn MID49 and MID51.

Uniprot	O00429
Gene Name	DNM1L
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:10059
Unigene	Hs.556296

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803144	E14496h	96T	$736		Add to Cart

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