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Home / Assay Kits / ELISA Kits

ELISA Kit for Human DNA topoisomerase 2-beta

SKU : BHE13811150

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1188h
Alternative Names	DNA topoisomerase II ; beta isozyme
Categories	Elisa
Function	Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly ivolved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Specificity	Natural and recombinant Human DNA topoisomerase 2-beta
Subcellular Location	Cytoplasm Nucleus nucleolus
Detection Range	0.156-10ng/mL
Entryname	TOP2B_HUMAN
Method Type	Sandwich
Platform	PF00204
Protein Name	DNA topoisomerase 2-beta
Sensitivity	0.045ng/mL
Sequence	50: MAKSGGCGAG ; AGVGGGNGAL ; TWVTLFDQNN ; AAKKEESETA ; NKNDSSKKLS ; 100: VERVYQKKTQ ; LEHILLRPDT ; YIGSVEPLTQ ; FMWVYDEDVG ; MNCREVTFVP ; 150: GLYKIFDEIL ; VNAADNKQRD ; KNMTCIKVSI ; DPESNIISIW ; NNGKGIPVVE ; 200: HKVEKVYVPA ; LIFGQLLTSS ; NYDDDEKKVT ; GGRNGYGAKL ; CNIFSTKFTV ; 250: ETACKEYKHS ; FKQTWMNNMM ; KTSEAKIKHF ; DGEDYTCITF ; QPDLSKFKME ; 300: KLDKDIVALM ; TRRAYDLAGS ; CRGVKVMFNG ; KKLPVNGFRS ; YVDLYVKDKL ; 350: DETGVALKVI ; HELANERWDV ; CLTLSEKGFQ ; QISFVNSIAT ; TKGGRHVDYV ; 400: VDQVVGKLIE ; VVKKKNKAGV ; SVKPFQVKNH ; IWVFINCLIE ; NPTFDSQTKE ; 450: NMTLQPKSFG ; SKCQLSEKFF ; KAASNCGIVE ; SILNWVKFKA ; QTQLNKKCSS ; 500: VKYSKIKGIP ; KLDDANDAGG ; KHSLECTLIL ; TEGDSAKSLA ; VSGLGVIGRD ; 550: RYGVFPLRGK ; ILNVREASHK ; QIMENAEINN ; IIKIVGLQYK ; KSYDDAESLK ; 600: TLRYGKIMIM ; TDQDQDGSHI ; KGLLINFIHH ; NWPSLLKHGF ; LEEFITPIVK ; 650: ASKNKQELSF ; YSIPEFDEWK ; KHIENQKAWK ; IKYYKGLGTS ; TAKEAKEYFA ; 700: DMERHRILFR ; YAGPEDDAAI ; TLAFSKKKID ; DRKEWLTNFM ; EDRRQRRLHG ; 750: LPEQFLYGTA ; TKHLTYNDFI ; NKELILFSNS ; DNERSIPSLV ; DGFKPGQRKV ; 800: LFTCFKRNDK ; REVKVAQLAG ; SVAEMSAYHH ; GEQALMMTIV ; NLAQNFVGSN ; 850: NINLLQPIGQ ; FGTRLHGGKD ; AASPRYIFTM ; LSTLARLLFP ; AVDDNLLKFL ; 900: YDDNQRVEPE ; WYIPIIPMVL ; INGAEGIGTG ; WACKLPNYDA ; REIVNNVRRM ; 950: LDGLDPHPML ; PNYKNFKGTI ; QELGQNQYAV ; SGEIFVVDRN ; TVEITELPVR ; 1000: TWTQVYKEQV ; LEPMLNGTDK ; TPALISDYKE ; YHTDTTVKFV ; VKMTEEKLAQ ; 1050: AEAAGLHKVF ; KLQTTLTCNS ; MVLFDHMGCL ; KKYETVQDIL ; KEFFDLRLSY ; 1100: YGLRKEWLVG ; MLGAESTKLN ; NQARFILEKI ; QGKITIENRS ; KKDLIQMLVQ ; 1150: RGYESDPVKA ; WKEAQEKAAE ; EDETQNQHDD ; SSSDSGTPSG ; PDFNYILNMS ; 1200: LWSLTKEKVE ; ELIKQRDAKG ; REVNDLKRKS ; PSDLWKEDLA ; AFVEELDKVE ; 1250: SQEREDVLAG ; MSGKAIKGKV ; GKPKVKKLQL ; EETMPSPYGR ; RIIPEITAMK ; 1300: ADASKKLLKK ; KKGDLDTAAV ; KVEFDEEFSG ; APVEGAGEEA ; LTPSVPINKG ; 1350: PKPKREKKEP ; GTRVRKTPTS ; SGKPSAKKVK ; KRNPWSDDES ; KSESDLEETE ; 1400: PVVIPRDSLL ; RRAAAERPKY ; TFDFSEEEDD ; DADDDDDDNN ; DLEELKVKAS ; 1450: PITNDGEDEF ; VPSDGLDKDE ; YTFSPGKSKA ; TPEKSLHDKK ; SQDFGNLFSF ; 1500: PSYSQKSEDD ; SAKFDSNEED ; SASVFSPSFG ; LKQTDKVPSK ; TVAAKKGKPS ; 1550: SDTVPKPKRA ; PKQKKVVEAV ; NSDSDSEFGI ; PKKTTTPKGK ; GRGAKKRKAS ; 1600: GSENEGDYNP ; GRKTSKTTSK ; KPKKTSFDQD ; SDVDIFPSDF ; PTEPPSLPRT ; 1626: GRARKEVKYF ; AESDEEEDDV ; DFAMFN
Sequence Length	1626
String	Q02880
Sub Unit	Homodimer. Component of the WINAC complex, at least composed of SMARCA2, SMARCA4, SMARCB1, SMARCC1, SMARCC2, SMARCD1, SMARCE1, ACTL6A, BAZ1B/WSTF, ARID1A, SUPT16H, CHAF1A and TOP2B.

Uniprot	Q02880
Gene Name	TOP2B
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:7155
Unigene	Hs.475733

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811150	E1188h	96T	$736		Add to Cart

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