Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Specificity
Natural and recombinant Human Cytochrome P450 3A5
Subcellular Location
Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein