11-beta-hydroxysteroid dehydrogenase 1 ; 11-DH ; Short chain dehydrogenase/reductase family 26C member 1 ; HSD11 ; HSD11L ; SDR26C1
Categories
Elisa
Function
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol.
Specificity
Natural and recombinant Human Corticosteroid 11-beta-dehydrogenase isozyme 1
Subcellular Location
Endoplasmic reticulum membrane Single-pass type II membrane protein