Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions.
Specificity
Natural and recombinant Human Cell adhesion molecule 3
Subcellular Location
Cell junction Cell membrane Single-pass type I membrane protein Localized at the cell-cell attached sites of the plasma membrane.