IP90 ; Major histocompatibility complex class I antigen-binding protein p88 ; p90
Categories
Elisa
Function
Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.
Specificity
Natural and recombinant Human Calnexin
Subcellular Location
Endoplasmic reticulum membrane Single-pass type I membrane protein Melanosome Identified by mass spectrometry in melanosome fractions from stage I to stage IV.