Annexin II ; Annexin-2 ; Calpactin I heavy chain ; Calpactin-1 heavy chain ; Chromobindin-8 ; Lipocortin II ; Placental anticoagulant protein IV ; PAP-IV ; Protein I ; p36 ; ANX2 ; ANX2L4 ; CAL1H ; LPC2D
Categories
Elisa
Function
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
Specificity
Natural and recombinant Human Annexin A2
Subcellular Location
Secreted extracellular space extracellular matrix basement membrane Melanosome In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.
Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with ATP1B1 and DYSF (By similarity). Interacts with human cytomegalovirus (HCMV).