Short peptide from AAT (SPAAT) is a reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
Specificity
Natural and recombinant Human Alpha-1-antitrypsin
Subcellular Location
Short peptide from AAT Secreted extracellular space extracellular matrix