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Home / Assay Kits / ELISA Kits

ELISA Kit for Human 25-hydroxycholesterol 7-alpha-hydroxylase

SKU : BHE13803364

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10333h
Alternative Names	Cytochrome P450 7B1 ; Oxysterol 7-alpha-hydroxylase
Categories	Elisa
Specificity	Natural and recombinant Human 25-hydroxycholesterol 7-alpha-hydroxylase
Subcellular Location	Endoplasmic reticulum membrane Peripheral membrane protein Microsome membrane Peripheral membrane protein
Detection Range	31.2-2000pg/mL
Entryname	CP7B1_HUMAN
Method Type	Sandwich
Platform	PF00067
Protein Name	25-hydroxycholesterol 7-alpha-hydroxylase
Sensitivity	15.68pg/mL
Sequence	50: MAGEVSAATG ; RFSLERLGLP ; GLALAAALLL ; LALCLLVRRT ; RRPGEPPLIK ; 100: GWLPYLGVVL ; NLRKDPLRFM ; KTLQKQHGDT ; FTVLLGGKYI ; TFILDPFQYQ ; 150: LVIKNHKQLS ; FRVFSNKLLE ; KAFSISQLQK ; NHDMNDELHL ; CYQFLQGKSL ; 200: DILLESMMQN ; LKQVFEPQLL ; KTTSWDTAEL ; YPFCSSIIFE ; ITFTTIYGKV ; 250: IVCDNNKFIS ; ELRDDFLKFD ; DKFAYLVSNI ; PIELLGNVKS ; IREKIIKCFS ; 300: SEKLAKMQGW ; SEVFQSRQDV ; LEKYYVHEDL ; EIGAHHLGFL ; WASVANTIPT ; 350: MFWAMYYLLR ; HPEAMAAVRD ; EIDRLLQSTG ; QKKGSGFPIH ; LTREQLDSLI ; 400: CLESSIFEAL ; RLSSYSTTIR ; FVEEDLTLSS ; ETGDYCVRKG ; DLVAIFPPVL ; 450: HGDPEIFEAP ; EEFRYDRFIE ; DGKKKTTFFK ; RGKKLKCYLM ; PFGTGTSKCP ; 500: GRFFALMEIK ; QLLVILLTYF ; DLEIIDDKPI ; GLNYSRLLFG ; IQYPDSDVLF ; 506: RYKVKS
Sequence Length	506
String	O75881

Uniprot	O75881
Gene Name	CYP7B1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:9420
Unigene	Hs.667720

Reference	1. "Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7-alpha-hydroxylase gene causes severe neonatal liver disease." Setchell K.D.R., Schwarz M., O'Connell N.C., Lund E.G., Davis D.L., Lathe R., Thompson H.R., Tyson W.R., Sokol R.J., Russell D.W. J. Clin. Invest.102:1690-1703(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INVOLVEMENT IN CBAS3 tissue: Liver. tissue: Spleen. 2. "Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1." Wu Z.L., Martin K.O., Javitt N.B., Chiang J.Y.L. J. Lipid Res.40:2195-2203(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] tissue: Hippocampus. 3. Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.more... Submitted (2005-07) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 5. "Sequence alterations within CYP7B1 implicate defective cholesterol homeostasis in motor-neuron degeneration." Tsaousidou M.K., Ouahchi K., Warner T.T., Yang Y., Simpson M.A., Laing N.G., Wilkinson P.A., Madrid R.E., Patel H., Hentati F., Patton M.A., Hentati A., Lamont P.J., Siddique T., Crosby A.H. Am. J. Hum. Genet.82:510-515(2008) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SPG5A ARG-57; SER-216; PHE-363 AND HIS-417

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803364	E10333h	96T	$736		Add to Cart

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