Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury.
Specificity
Natural and recombinant Dog Uveal autoantigen with coiled-coil domains and ankyrin repeats
Subcellular Location
Nucleus Cytoplasm Cytoplasm cytoskeleton Expressed diffusely in cytoplasm.
Entryname
UACA_CANFA
Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of UACA and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤5.8%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤7.9%
Protein Name
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Recovery
Recovery was determined by spiking various levels of UACA into serum and plasma .
Component of the apoptosome complex, composed of APAF1, pro-caspase-9 and UACA. In the complex, it probably interacts directly with APAF1. Interacts with LGALS3, ARF6 and ACTB.