ELISA Kit for Dog Transcription factor GATA-4

Mfr.No.	E0374d
Alternative Names	GATA-binding factor 4
Categories	Elisa
Function	Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement.
Specificity	Natural and recombinant Dog Transcription factor GATA-4
Subcellular Location	Nucleus
Entryname	GATA4_CANFA
Platform	PF00320
Protein Name	Transcription factor GATA-4
Sequence	50: MYQSLAMAAN ; HGPPPGAYEA ; GGPGAFMHGA ; GAASSPVYVP ; TPRVPSSVLG ; 100: LSYLQGGGGA ; AASGASSGGG ; SGGAPSAAGP ; GAQQGSPGWS ; QAGADGAAYT ; 150: PPPVSPRFSF ; PGTTGSLAAA ; AAAAAAREAA ; AYGGGGGAAG ; AGLAGREQYG ; 200: RAGFAGSYSS ; PYPAYMADVG ; ASWAAAAAAS ; AGPFDSPVLH ; SLPGRANPAA ; 250: RHPNLDMFDD ; FSEGRECVNC ; GAMSTPLWRR ; DGTGHYLCNA ; CGLYHKMNGI ; 300: NRPLIKPQRR ; LSASRRVGLS ; CANCQTTTTT ; LWRRNAEGEP ; VCNACGLYMK ; 350: LHGVPRPLAM ; RKEGIQTRKR ; KPKNLNKSKT ; PAGPSGGESL ; PPASSASSNS ; 400: SNVATSSSEE ; MRPIKTEPGL ; SSHYGHSSSM ; SQTFSVSAMS ; GHGPSIHPVL ; 442: SALKLSPQGY ; TSSVSQSPQA ; SSKQDPWNSL ; ALADSHGDII ; TA
Sequence Length	442
String	Q0Q0E4
Sub Unit	Interacts with ZNF260 (By similarity). Interacts with the homeobox domain of NKX2-5 through its C-terminal zinc finger. Also interacts with JARID2 which represses its ability to activate transcription of ANF. Interacts with NFATC4 and LMCD1. Forms a complex made of CDK9, CCNT1/cyclin-T1, EP300 and GATA4 that stimulates hypertrophy in cardiomyocytes.

Reference	1. "Molecular screening of GATA4 gene in canine atrial septal defects." Hyun C., Lee S.-A., Lee S.-G. Submitted (2006-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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BHE13804508	E0374d	96T	$900		Add to Cart