ELISA Kit for Dog Melanocyte-stimulating hormone receptor

Mfr.No.	E9983d
Alternative Names	Melanocortin receptor 1 ; MC1-R
Categories	Elisa
Function	Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Could be involved in spermatogenesis.
Specificity	Natural and recombinant Dog Melanocyte-stimulating hormone receptor
Subcellular Location	Cell membrane Multi-pass membrane protein
Entryname	MSHR_CANFA
Platform	PF00001
Protein Name	Melanocyte-stimulating hormone receptor
Sequence	50: MVWQGPQRRL ; LGSLNGTSPA ; TPHFELAANQ ; TGPRCLEVSI ; PNGLFLSLGL ; 100: VSVVENVLVV ; AAIAKNRNLH ; SPMYYFIGCL ; AVSDLLVSVT ; NVLETAVMLL ; 150: VEAGALAAQA ; AVVQQLDDII ; DVLICGSMVS ; SLCFLGAIAV ; DRYLSIFYAL ; 200: RYHSIVTLPR ; AWRAISAIWV ; ASVLSSTLFI ; AYYNHTAVLL ; CLVSFFVAML ; 250: VLMAVLYVHM ; LARARQHARG ; IARLRKRQHS ; VHQGFGLKGA ; ATLTILLGIF ; 300: FLCWGPFFLH ; LSLMVLCPQH ; PICGCVFQNF ; NLFLTLIICN ; SIIDPFIYAF ; 317: RSQELRKTLQ ; EVVLCSW
Sequence Length	317
String	O77616
Sub Unit	Interacts with MGRN1, but does not undergo MGRN1-mediated ubiquination; this interaction competes with GNAS-binding and thus inhibits agonist-induced cAMP production.

Reference	1. "Identification of a premature stop codon in the melanocyte-stimulating hormone receptor gene (MC1R) in Labrador and Golden retrievers with yellow coat colour." Everts R.E., Rothuizen J., van Oost B.A. Anim. Genet.31:194-199(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT 306-ARG--TRP-317 DEL

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805969	E9983d	96T	$900		Add to Cart