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Home / Assay Kits / ELISA Kits

ELISA Kit for Chicken Tyrosine-protein kinase JAK2

SKU : BHE13806217

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9140c
Alternative Names	Janus kinase 2 ; JAK-2
Categories	Elisa
Function	Non-receptor tyrosine kinase involved in various processes such as cell cycle progression, apoptosis, mitotic recombination, genetic instability and histone modifications. In the cytoplasm, plays a pivotal role in signal transduction via its association with cytokine receptors, which constitutes an initiating step in signaling for many members of the cytokine receptor superfamily. Following stimulation with erythropoietin (EPO) during erythropoiesis, it is autophosphorylated and activated, leading to its association with erythropoietin receptor (EPOR) and tyrosine phosphorylation of residues in the EPOR cytoplasmic domain. Also involved in promoting the localization of EPOR to the plasma membrane. In the nucleus, plays a key role in chromatin by specifically mediating phosphorylation of 'Tyr-41' of histone H3 (H3Y41ph), a specific tag that promotes exclusion of CBX5 (HP1 alpha) from chromatin.
Specificity	Natural and recombinant Chicken Tyrosine-protein kinase JAK2
Subcellular Location	Endomembrane system Peripheral membrane protein Nucleus
Entryname	JAK2_CHICK
Method Type	Sandwich
Platform	PF07714
Protein Name	Tyrosine-protein kinase JAK2
Sequence	50: MACLTMANIE ; GSATATVHQN ; GDILGNTSAP ; KQTEPLLQVY ; LYYSPGKTGG ; 100: DYLQFPAGEY ; VAEEICIVAC ; KACGIMPVYH ; NMFALMSETE ; RVWYPPNHIF ; 150: HVDEATRLKL ; LYRIRFYFPH ; WYCNGTSRAC ; RYGIIRGSES ; PVLDDLVMSY ; 200: LFAQWRKDFL ; DGWIQMPVTH ; ETQEECLGMA ; VLDMMRVAKE ; KDQTPLAVYN ; 250: SVSYKMFLPK ; CVRAKIQEYH ; ILTRKRIRYR ; FRKFIQQFGQ ; CKATARNLKL ; 300: KYLINLETLQ ; SAFYSEVFEV ; KEPGGDPSGE ; ESFATIVITG ; NGGIQCSRGK ; 350: LKNCETLAEQ ; DLQTYCDFPD ; IIDVSIKQAS ; QEGSSERRIV ; TIHKQDSKNL ; 400: EAEFQSLREA ; LSFVSLIDGY ; YRLTADAHHY ; LCKEVAPPSV ; LENIQSNCHG ; 450: PIFMDFAINK ; LKKAGNQTGF ; YVLRCSPKDF ; KKYFLTFAIE ; RENATDYKHC ; 500: LITKNENGEY ; NLSGTKRSFG ; NLKDLLTCYQ ; TETVRSDSII ; FQFIKCCPPK ; 550: PKDKSNLLVF ; RSNSVSDVPS ; SPTLQRHNVS ; QMVFHKIRNE ; DLIFEESLGQ ; 600: GTFTKIFKGI ; RKEVGDYGQL ; HQTEVLLKVL ; DKVHRNYSES ; FFEAASMMSQ ; 650: LSYKHLVLNY ; GVCVCGEENI ; LVQEYVKFGS ; LDTYLKKNKN ; VINILWKLEV ; 700: AKQLALAMHF ; LEDKGLVHGN ; VCAKNILLIR ; EEDRKSGNLP ; FIKLSDPGIS ; 750: ITVLPRDILL ; ERIPWVPPEC ; IENPRQLSLA ; TDKWSFGTTL ; WEICSGGDKP ; 800: LSALDSSRKL ; QFYEDRHQLP ; APNWTELANL ; INNCMDYEPD ; FRPSFRAIIR ; 850: DLNSLFTPDY ; ELLTENDMLP ; NIRTGALGFS ; GAFEDRDPTQ ; FEERHLKFLQ ; 900: QLGKGNFGSV ; EMCRYDPLQD ; NTGEVVAVKK ; LQHSTEEHLR ; DFEREIEILK ; 950: SLQHDNIVKY ; KGVCYSAGRR ; NLRLIMEYLP ; YGSLRDYLQK ; HKERLDHKKL ; 1000: LLYASQICKG ; MEYLGTKRYV ; HRDLATRNIL ; VENENRVKIG ; DFGLTKVLPQ ; 1050: DKEYYKVKEP ; GESPIFWYAP ; ESLTESKFSV ; ASDVWSFGVV ; LYELFTYIEK ; 1100: SKSPPAEFMR ; MIGNDKQGQM ; IVFHLIELLK ; NNGRLPRPDG ; CPDEIYAIMK ; 1129: ECWNNNVAQR ; PTFRDLAQRV ; DQIRDNMGG
Sequence Length	1129
String	Q75R65

Uniprot	Q75R65
Gene Name	JAK2
Immunogen Species	Gallus Gallus (Chicken)
Kegg	gga:374199
Unigene	Gga.954

Reference	1. "molecular cloning and characterization of chicken tyrosine kinase JAK-2." Sayed A.A., Horiuchi H., Furusawa S., Matsuda H. Submitted (2004-01) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: White leghorn. tissue: Spleen.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806217	E9140c	96T	$900		Add to Cart

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