Low-density lipoprotein receptor relative with 11 ligand-binding repeats ; LDLR relative with 11 ligand-binding repeats ; SorLA-1 ; Sorting protein-related receptor containing LDLR class A repeats ; SorLA
Categories
Elisa
Function
Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. Both estrogen status and cholesterol levels lack regulatory effects on this receptor.
Specificity
Natural and recombinant Chicken Sortilin-related receptor