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Home / Assay Kits / ELISA Kits

ELISA Kit for Chicken Protein DJ-1

SKU : BHE13809122

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3064c
Alternative Names	Parkinson disease protein 7 homolog ; Protein deglycase DJ-1 ; 3.1.2.-
Categories	Elisa
Function	Protects cells against oxidative stress and cell death. May act as an atypical peroxiredoxin-like peroxidase that scavenges hydrogen peroxide. Following removal of a C-terminal peptide, displays protease activity and enhanced cytoprotective action against oxidative stress-induced apoptosis. Binds to a number of mRNAs containing multiple copies of GG or CC motifs and partially inhibits their translation but dissociates following oxidative stress. Required for correct mitochondrial morphology and function and for autophagy of dysfunctional mitochondria. Regulates astrocyte inflammatory responses. Acts as a positive regulator of androgen receptor-dependent transcription. Prevents aggregation of SNCA. Plays a role in fertilization. Has no proteolytic activity. Has cell-growth promoting activity and transforming activity. May function as a redox-sensitive chaperone.
Specificity	Natural and recombinant Chicken Protein DJ-1
Subcellular Location	Cytoplasm Nucleus Mitochondrion Under normal conditions, located predominantly in the cytoplasm and, to a lesser extent, in the nucleus and mitochondrion. Translocates to the mitochondrion and subsequently to the nucleus in response to oxidative stress and exerts an increased cytoprotective effect against oxidative damage.
Entryname	PARK7_CHICK
Platform	PF01965
Protein Name	Protein DJ-1
Sequence	50: MASKRALVIL ; AKGAEEMETV ; IPTDVMRRAG ; IKVTVAGLTG ; KEPVQCSRDV ; 100: LICPDASLED ; ARKEGPYDVI ; VLPGGNLGAQ ; NLSESAAVKD ; ILKDQESRKG ; 150: LIAAICAGPT ; ALLAHGIGFG ; SKVITHPLAK ; DKMMNGAHYC ; YSESRVEKDG ; 189: NILTSRGPGT ; SFEFGLAIVE ; ALMGKEVAEQ ; VKAPLILKD
Sequence Length	189
String	Q8UW59
Sub Unit	Homodimer.

Uniprot	Q8UW59
Gene Name	PARK7
Immunogen Species	Gallus Gallus (Chicken)
Kegg	gga:395277
Unigene	Gga.3836

Reference	1. "Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities." Shinbo Y., Niki T., Taira T., Ooe H., Takahashi-Niki K., Maita C., Seino C., Iguchi-Ariga S.M.M., Ariga H. Cell Death Differ.13:96-108(2006) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809122	E3064c	96T	$900		Add to Cart

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