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Home / Assay Kits / ELISA Kits

ELISA Kit for Chicken Presenilin-2

SKU : BHE13809202

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1274c
Categories	Elisa
Function	Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Specificity	Natural and recombinant Chicken Presenilin-2
Subcellular Location	Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein
Entryname	PSN2_CHICK
Platform	PF01080
Protein Name	Presenilin-2
Sequence	50: MITFMNNSDS ; EDEPCNERTS ; LMSAESPPVP ; SYQDGLQASE ; TREAQTHRKR ; 100: QTGSSRSPNN ; VADEDASDSD ; VRVRESALEN ; EEEELTLKYG ; AKHVIMLFVP ; 150: VTLCMIVVVA ; TIKSVRFYTE ; KNGQLIYTPF ; SEDTPSVGQR ; LLNSVLNTII ; 200: MISVIVVMTV ; FLVVLYKYRC ; YKFIHGWLIL ; SSFMLLFLFT ; YIYLGEVLKT ; 250: YNVAMDYPTV ; ILIIWNFGAV ; GMIRIHWKGP ; LQLQQAYLIM ; ISALMVLVFI ; 300: KYLPEWSAWV ; ILGAISIYDL ; IAVLCPKGPL ; RMLXETAQER ; NQPIFPALIY ; 350: SSAMIWTVGM ; AKPDTAAKGQ ; SQQAWDAEDE ; RENHSSTSHS ; DSQILDTRSP ; 400: APSHPITLEE ; MEEEERGVKL ; GLGDFIFYSV ; LVGKAAATPS ; GDWNTTLAXX ; 450: VAILIGLCLT ; LLLLAVFKKA ; LPALPISITF ; GLIFYFSTDN ; LVRTDPLEIS ; 451: V
Sequence Length	451
String	Q90X07
Sub Unit	Homodimer. Component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. Such minimal complex is sufficient for secretase activity, although other components may exist.

Uniprot	Q90X07
Gene Name	PSEN2
Immunogen Species	Gallus Gallus (Chicken)
Kegg	gga:374188
Unigene	Gga.2719

Reference	1. "Identification of the presenilins in hematopoietic cells with localization of presenilin 1 to neutrophil and platelet granules." Mirinics Z.K., Calafat J., Udby L., Lovelock J., Kjeldsen L., Rothermund K., Sisodia S.S., Borregaard N., Corey S.J. Blood Cells Mol. Dis.28:28-38(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: B-cell.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809202	E1274c	96T	$900		Add to Cart

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