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Home / Assay Kits / ELISA Kits

ELISA Kit for Chicken Integrin beta-1

SKU : BHE13806310

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2224c
Alternative Names	CSAT antigen ; JG22 antigen ; RGD-receptor
Categories	Elisa
Function	Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-1 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and GNB2L1, serves as a platform for SRC activation or inactivation.
Specificity	Natural and recombinant Chicken Integrin beta-1
Subcellular Location	Cell membrane Single-pass type I membrane protein Melanosome
Detection Range	78-5000pg/mL
Entryname	ITB1_CHICK
Method Type	Sandwich
Platform	PF07974
Protein Name	Integrin beta-1
Sensitivity	39.5 pg/mL
Sequence	50: MAETNLTLLT ; WAGILCCLIW ; SGSAQQGGSD ; CIKANAKSCG ; ECIQAGPNCG ; 100: WCKKTDFLQE ; GEPTSARCDD ; LAALKSKGCP ; EQDIENPRGS ; KRVLEDREVT ; 150: NRKIGAAEKL ; KPEAITQIQP ; QKLVLQLRVG ; EPQTFSLKFK ; RAEDYPIDLY ; 200: YLMDLSYSMK ; DDLENVKSLG ; TALMREMEKI ; TSDFRIGFGS ; FVEKTVMPYI ; 250: STTPAKLRNP ; CTGDQNCTSP ; FSYKNVLSLT ; SEGNKFNELV ; GKQHISGNLD ; 300: SPEGGFDAIM ; QVAVCGDQIG ; WRNVTRLLVF ; STDAGFHFAG ; DGKLGGIVLP ; 350: NDGKCHLENN ; MYTMSHYYDY ; PSIAHLVQKL ; SENNIQTIFA ; VTEEFQAVYK ; 400: ELKNLIPKSA ; VGTLSSNSSN ; VIQLIIDAYN ; SLSSEVILEN ; SKLPKEVTIS ; 450: YKSYCKNGVN ; DTQEDGRKCS ; NISIGDEVRF ; EINVTANECP ; KKGQNETIKI ; 500: KPLGFTEEVE ; IHLQFICDCL ; CQSEGEPNSP ; ACHDGNGTFE ; CGACRCNEGR ; 550: IGRLCECSTD ; EVNSEDMDAY ; CRRENSTEIC ; SNNGECICGQ ; CVCKKRENTN ; 600: EVYSGKYCEC ; DNFNCDRSNG ; LICGGNGICK ; CRVCECFPNF ; TGSACDCSLD ; 650: TTPCMAGNGQ ; ICNGRGTCEC ; GTCNCTDPKF ; QGPTCEMCQT ; CLGVCAEHKD ; 700: CVQCRAFEKG ; EKKETCSQEC ; MHFNMTRVES ; RGKLPQPVHP ; DPLSHCKEKD ; 750: VGDCWFYFTY ; SVNSNGEASV ; HVVETPECPS ; GPDIIPIVAG ; VVAGIVLIGL ; 800: ALLLIWKLLM ; IIHDRREFAK ; FEKEKMNAKW ; DTGENPIYKS ; AVTTVVNPKY ; 803: EGK
Sequence Length	803
String	P07228
Sub Unit	Heterodimer of an alpha and a beta subunit. Beta-1 associates with either alpha-1, alpha-2, alpha-3, alpha-4, alpha-5, alpha-6, alpha-7, alpha-8, alpha-9, alpha-10, alpha-11 or alpha-V.

Uniprot	P07228
Gene Name	ITGB1
Immunogen Species	Gallus Gallus (Chicken)
Unigene	Gga.111

Reference	1. "Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin." Tamkun J.W., Desimone D.W., Fonda D., Patel R.S., Buck C., Horwitz A.F., Hynes R.O. Cell46:271-282(1986) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY tissue: Embryonic fibroblast.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806310	E2224c	96T	$900		Add to Cart

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