ELISA Kit for Chicken Heparanase

Mfr.No.	E0711c
Alternative Names	HPA
Categories	Elisa
Function	Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling (By similarity). Increases cell adhesion to the extacellular matrix (ECM), independent of its enzymatic activity.
Specificity	Natural and recombinant Chicken Heparanase
Subcellular Location	Secreted Localized close to cell surface.
Entryname	HPSE_CHICK
Platform	PF03662
Protein Name	Heparanase
Sequence	50: MLVLLLLVLL ; LAVPPRRTAE ; LQLGLREPIG ; AVSPAFLSLT ; LDASLARDPR ; 100: FVALLRHPKL ; HTLASGLSPG ; FLRFGGTSTD ; FLIFNPNKDS ; TWEEKVLSEF ; 150: QAKDVCEAWP ; SFAVVPKLLL ; TQWPLQEKLL ; LAEHSWKKHK ; NTTITRSTLD ; 200: ILHTFASSSG ; FRLVFGLNAL ; LRRAGLQWDS ; SNAKQLLGYC ; AQRSYNISWE ; 250: LGNEPNSFRK ; KSGICIDGFQ ; LGRDFVHLRQ ; LLSQHPLYRH ; AELYGLDVGQ ; 300: PRKHTQHLLR ; SFMKSGGKAI ; DSVTWHHYYV ; NGRSATREDF ; LSPEVLDSFA ; 350: TAIHDVLGIV ; EATVPGKKVW ; LGETGSAYGG ; GAPQLSNTYV ; AGFMWLDKLG ; 400: LAARRGIDVV ; MRQVSFGAGS ; YHLVDAGFKP ; LPDYWLSLLY ; KRLVGTRVLQ ; 450: ASVEQADARR ; PRVYLHCTNP ; RHPKYREGDV ; TLFALNLSNV ; TQSLQLPKQL ; 500: WSKSVDQYLL ; LPHGKDSILS ; REVQLNGRLL ; QMVDDETLPA ; LHEMALAPGS ; 523: TLGLPAFSYG ; FYVIRNAKAI ; ACI
Sequence Length	523
String	Q90YK5
Sub Unit	Heterodimer; the active enzyme is a heterodimer of the 60 kDa and 45 kDa proteolytic products.

Reference	1. "Expression pattern and secretion of human and chicken heparanase are determined by their signal peptide sequence." Goldshmidt O., Zcharia E., Aingorn H., Guatta-Rangini Z., Atzmon R., Michal I., Pecker I., Mitrani E., Vlodavsky I. J. Biol. Chem.276:29178-29187(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;SUBUNIT;ENZYME ACTIVITY;DEVELOPMENTAL STAGE 2. "Heparanase mediates cell adhesion independent of its enzymatic activity." Goldshmidt O., Zcharia E., Cohen M., Aingorn H., Cohen I., Nadav L., Katz B.Z., Geiger B., Vlodavsky I. FASEB J.17:1015-1025(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805349	E0711c	96T	$900		Add to Cart