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Home / Assay Kits / ELISA Kits

ELISA Kit for Chicken Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

SKU : BHE13805401

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1916c
Alternative Names	Histone arginine demethylase JMJD6 ; JmjC domain-containing protein 6 ; Jumonji domain-containing protein 6 ; Lysyl-hydroxylase JMJD6 ; Peptide-lysine 5-dioxygenase JMJD6 ; Phosphatidylserine receptor ; Protein PTDSR ; PTDSR ; RCJMB04_1m8
Categories	Elisa
Function	Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as a RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which demethylates histone H3 at 'Arg-2' (H3R2me) and histone H4 at 'Arg-3' (H4R3me), thereby playing a role in histone code. However, histone arginine demethylation may not constitute the primary activity in vivo. Has no histone lysine demethylase activity. Required for differentiation of multiple organs during embryogenesis. Acts as a key regulator of hematopoietic differentiation.
Specificity	Natural and recombinant Chicken Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Subcellular Location	Nucleus nucleoplasm Nucleus nucleolus
Entryname	JMJD6_CHICK
Platform	PF02373
Protein Name	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Sequence	50: MNHKSKKRIR ; EAKRSARPEL ; KDSLDWTRHN ; YCETFPLSPA ; ACKDNVERAD ; 100: ALQLTVEEFV ; ERYEKPYKPV ; VLLNAQVGWS ; AQEKWTLERL ; KRKYRNQKFK ; 150: CGEDNDGYSV ; KMKMKYYIEY ; METTRDDSPL ; YIFDSSYGEH ; PKRRKLLEDY ; 200: KVPKFFTDDL ; FQYAGEKRRP ; PYRWFVMGPP ; RSGTGIHIDP ; LGTSAWNALV ; 250: QGHKRWCLFP ; TSTPRELIKV ; AREEGGNQQD ; EAITWFNVIY ; PRTQLPTWPP ; 300: EFKPLEILQK ; PGETVFVPGG ; WWHVVLNLDT ; TIAITQNFAS ; CTNFPVVWHK ; 350: TVRGRPKLSR ; KWYRILKQEH ; PDLAALADSV ; DLQESTGIAS ; DSSSDSSSSS ; 400: SSSSSDSDSE ; CDSGSETEGM ; MHRRKKRRTC ; SMMGNGDTTS ; QDDCVSKERS ; 414: SSRIRESCGG ; RSYP
Sequence Length	414

Uniprot	Q5ZMK5
Gene Name	JMJD6
Immunogen Species	Gallus Gallus (Chicken)
Kegg	gga:417355
Unigene	Gga.21114

Reference	1. "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis." Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P., Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P., Hayashizaki Y., Buerstedde J.-M. Genome Biol.6:R6.1-R6.9(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: CB. tissue: Bursa of Fabricius.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805401	E1916c	96T	$900		Add to Cart

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