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ELISA Kit for Bovine Toll-like receptor 3

SKU : BHE13811314

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1989b
Alternative Names	CD283
Categories	Elisa
Function	Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Specificity	Natural and recombinant Bovine Toll-like receptor 3
Subcellular Location	Endoplasmic reticulum membrane Single-pass type I membrane protein Endosome membrane
Entryname	TLR3_BOVIN
Platform	PF00560
Protein Name	Toll-like receptor 3
Sequence	50: MSRPLPYHIH ; FFSGLLTCWI ; LCTSSAHKCT ; VRHEVADCSH ; LKLTQIPDDL ; 100: PTNITVLNLT ; HNQLRRLPPA ; NFTRYSQLTT ; LDGGFNSISK ; LEPELCQSLP ; 150: WLEILNLQHN ; EISQLSDKTF ; IFCMNLTELH ; LMSNSIQKIK ; NDPFKNLKNL ; 200: IKLDLSHNGL ; SSTKLGTQLQ ; LENLQELLLS ; NNKISSLTPG ; EFDFLGNSSL ; 250: KRLELSSNQI ; KEFSPGCFHT ; LGELSGLSLN ; NAKLSPSLTE ; KLCLELSNTS ; 300: IENLSLSSNQ ; LDTISHTTFD ; GLKQTNLTTL ; DLSRNSLRVM ; GNDSFAWLPH ; 350: LEYLSLEYNN ; IEHLSSRSFY ; GLSNLRRLDL ; RRSFTRQSIS ; LTSLPKIDDF ; 400: SFQWLKCLEY ; LNMDDNNFPG ; IKRNTFTGLV ; RLKFLSLSNS ; FSSLRTLTNE ; 450: TFLSLAGCPL ; LLLDLTKNKI ; SKIQSGAFSW ; LGHLEVLDLG ; LNEIGQELTG ; 500: QEWRGLDNIV ; EIYLSYNKYL ; ELTTNSFTSV ; PSLQRLMLRR ; VALKNVDCSP ; 550: SPFRPLPNLV ; ILDLSNNNIA ; NINDELLKGL ; EKLEILDLQH ; NNLARLWKHA ; 600: NPGGPVQFLK ; GLFHLHILNL ; GSNGFDEIPV ; EAFKDLRELK ; SIDLGMNNLN ; 650: ILPQSVFDNQ ; VSLKSLSLQK ; NLITSVQKTV ; FGPAFRNLSY ; LDMRFNPFDC ; 700: TCESIAWFVN ; WINITHTNIS ; ELSNHYLCNT ; PPQYHGYPVM ; LFDVSPCKDS ; 750: APFELLFMIN ; INILLIFIFI ; VLLIHFEGWR ; ISFYWNVSVH ; RVLGFKEIDR ; 800: AEQFEYAAYI ; IHAYKDRDWV ; WKHSSPMEDE ; DHTLRFCLEE ; RDFEAGVLEL ; 850: EAIVNSIRRS ; RKIIFVVTQN ; LLKDPLCKRF ; KVHHAVQQAI ; EQNLDSIILI ; 900: FLEEIPDYKL ; NHALCLRRGM ; FKSHCILNWP ; VQKERVNAFH ; HKLKVALGSR ; 904: NSAH
Sequence Length	904
String	Q5TJ59
Sub Unit	Binds MYD88 via their respective TIR domains. Interacts with TICAM1. Homodimer formation is triggered by ligand binding and is required for TLR3 signaling. Binding of double-stranded RNA is required for the interaction with SRC. Interacts (via transmembrane domain) with UNC93B1.

Uniprot	Q5TJ59
Gene Name	TLR3
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:281535
Unigene	Bt.12298

Reference	1. "Molecular characterization of the bovine TLR3-encoding gene reveals expression from alternative promoters." Yang W., Werling D., Goldammer T., Seyfert H.M. Submitted (2004-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Mammary gland.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811314	E1989b	96T	$900		Add to Cart

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