ELISA Kit for Bovine Steroid 17-alpha-hydroxylase/17,20 lyase

Mfr.No.	E2016b
Alternative Names	17-alpha-hydroxyprogesterone aldolase ; CYPXVII ; Cytochrome P450 17A1 ; Cytochrome P450-C17 ; Cytochrome P450c17 ; CYP17
Categories	Elisa
Function	Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
Specificity	Natural and recombinant Bovine Steroid 17-alpha-hydroxylase/17,20 lyase
Subcellular Location	Membrane
Entryname	CP17A_BOVIN
Platform	PF00067
Protein Name	Steroid 17-alpha-hydroxylase/17,20 lyase
Sequence	50: MWLLLAVFLL ; TLAYLFWPKT ; KHSGAKYPRS ; LPSLPLVGSL ; PFLPRRGQQH ; 100: KNFFKLQEKY ; GPIYSFRLGS ; KTTVMIGHHQ ; LAREVLLKKG ; KEFSGRPKVA ; 150: TLDILSDNQK ; GIAFADHGAH ; WQLHRKLALN ; AFALFKDGNL ; KLEKIINQEA ; 200: NVLCDFLATQ ; HGEAIDLSEP ; LSLAVTNIIS ; FICFNFSFKN ; EDPALKAIQN ; 250: VNDGILEVLS ; KEVLLDIFPV ; LKIFPSKAME ; KMKGCVQTRN ; ELLNEILEKC ; 300: QENFSSDSIT ; NLLHILIQAK ; VNADNNNAGP ; DQDSKLLSNR ; HMLATIGDIF ; 350: GAGVETTTSV ; IKWIVAYLLH ; HPSLKKRIQD ; DIDQIIGFNR ; TPTISDRNRL ; 400: VLLEATIREV ; LRIRPVAPTL ; IPHKAVIDSS ; IGDLTIDKGT ; DVVVNLWALH ; 450: HSEKEWQHPD ; LFMPERFLDP ; TGTQLISPSL ; SYLPFGAGPR ; SCVGEMLARQ ; 500: ELFLFMSRLL ; QRFNLEIPDD ; GKLPSLEGHA ; SLVLQIKPFK ; VKIEVRQAWK ; 509: EAQAEGSTP
Sequence Length	509
String	P05185

Reference	1. "Bovine adrenocortical cytochrome P-450(17 alpha). Regulation of gene expression by ACTH and elucidation of primary sequence." Zuber M.X., John M.E., Okamura T., Simpson E.R., Waterman M.R. J. Biol. Chem.261:2475-2482(1986) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Structural characterization of the bovine CYP17 (17 alpha-hydroxylase) gene." Bhasker C.R., Adler B.S., Dee A., John M.E., Kagimoto M., Zuber M.X., Ahlgren R., Wang X.D., Simpson E.R., Waterman M.R. Arch. Biochem. Biophys.271:479-487(1989) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 3. NIH - Mammalian Gene Collection (MGC) project Submitted (2005-11) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Crossbred X Angus. tissue: Liver.

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