Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm.
Specificity
Natural and recombinant Bovine Sorbitol dehydrogenase
Subcellular Location
Mitochondrion membrane Peripheral membrane protein Cell projection cilium flagellum Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.