ELISA Kit for Bovine Serine/threonine-protein kinase pim-1

Mfr.No.	E1997b
Categories	Elisa
Function	May affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3 (By similarity). Promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and proteasome-dependent degradation of CDKN1B (By similarity). Also represses CDKN1B transcription by phosphorylating and inactivating the transcription factor FOXO3 (By similarity). Plays a role in signal transduction in blood cells (By similarity). Contributes to both cell proliferation and survival thus providing a selective advantage in tumorigenesis.
Specificity	Natural and recombinant Bovine Serine/threonine-protein kinase pim-1
Subcellular Location	Cytoplasm Nucleus
Entryname	PIM1_BOVIN
Platform	PF00069
Protein Name	Serine/threonine-protein kinase pim-1
Sequence	50: MLLSKINSLA ; HLRAAPCSDL ; HATKLAPGKE ; KEPLESQYQV ; GPLLGSGGFG ; 100: SVYSGIRVAD ; NLPVAIKHVE ; KDRISDWGEL ; PNGTRVPMEV ; VLLKKVSSGF ; 150: SGVIRLLDWF ; ERPDSFVLIL ; ERPEPVQDLF ; DFITERGALQ ; EELARSFFWQ ; 200: VLEAVRHCHD ; CGVLHRDIKD ; ENILIDLNRG ; ELKLIDFGSG ; ALLKDTVYTD ; 250: FDGTRVYSPP ; EWIRYHRYHG ; RSAAVWSLGI ; LLYDMVCGDI ; PFEHDEEIVR ; 300: GQVFFRQRVS ; SECQHLIRWC ; LALRPSDRPT ; FEEIQNHPWM ; QDVLLPQETA ; 313: EIHLHSLSPG ; PSK
Sequence Length	313
String	Q9N0P9
Sub Unit	Binds to RP9 (By similarity). Interacts with CDKN1B and FOXO3.

Reference	1. "cDNA cloning, sequencing and characterization of bovine pim-1." Wang Z., Petersen K., Weaver M.S., Magnuson N.S. Vet. Immunol. Immunopathol.78:177-195(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808806	E1997b	96T	$900		Add to Cart