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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Serine/arginine-rich splicing factor 2

SKU : BHE13810544

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11550b
Alternative Names	Splicing component ; 35 kDa ; Splicing factor SC35 ; SC-35 ; Splicing factor ; arginine/serine-rich 2 ; SFRS2
Categories	Elisa
Function	Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway.
Specificity	Natural and recombinant Bovine Serine/arginine-rich splicing factor 2
Subcellular Location	Nucleus
Entryname	SRSF2_BOVIN
Method Type	Sandwich
Platform	PF00076
Protein Name	Serine/arginine-rich splicing factor 2
Sequence	50: MSYGRPPPDV ; EGMTSLKVDN ; LTYRTSPDTL ; RRVFEKYGRV ; GDVYIPRDRY ; 100: TKESRGFAFV ; RFHDKRDAED ; AMDAMDGAVL ; DGRELRVQMA ; RYGRPPDSHH ; 150: SRRGPPPRRY ; GGGGYGRRSR ; SPRRRRRSRS ; RSRSRSRSRS ; RSRYSRSKSR ; 200: SRTRSRSRST ; SKSRSARRSK ; SKSSSVSRSR ; SRSRSRSRSR ; SPPPVSKRES ; 221: KSRSRSKSPP ; KSPEEEGAVS ; S
Sequence Length	221
String	Q3MHR5
Sub Unit	In vitro, self-associates and binds SRSF1/SFRS1 (ASF/SF2), SNRNP70 and U2AF1 but not U2AF2. Binds SREK1/SFRS12. Interacts with CCNL1 and CCNL2. Interacts with SCAF11. Interacts with ZRSR2/U2AF1-RS2. Interacts with CCDC55 (via C-terminus).

Uniprot	Q3MHR5
Gene Name	SRSF2
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:508312
Unigene	Bt.2466

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2005-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Crossbred X Angus. tissue: Ileum.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810544	E11550b	96T	$900		Add to Cart

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