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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Secreted frizzled-related protein 1

SKU : BHE13809529

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1165b
Alternative Names	Frizzled in aorta protein ; FrzA protein ; FRZA
Categories	Elisa
Function	Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Specificity	Natural and recombinant Bovine Secreted frizzled-related protein 1
Subcellular Location	Secreted Cell membrane or extracellular matrix-associated. Released by heparin-binding.
Entryname	SFRP1_BOVIN
Platform	PF01392
Protein Name	Secreted frizzled-related protein 1
Sequence	50: MGGGRWAAAG ; ALLALAAGLL ; AAGSASEYDY ; VSFQSDIGAY ; QSGRFYTKPP ; 100: QCVDIPADLR ; LCHNVGYKRM ; VLPNLLEHET ; MAEVKQQASS ; WVPLLNKNCH ; 150: IGTQVFLCSL ; FAPVCLDRPI ; YPCRWLCEAV ; RDSCEPVMQF ; FGFYWPEMLK ; 200: CDKFPEGDVC ; IAMTPPNATE ; ASKPQGTTVC ; PPCDNELKSE ; AIIEHLCASE ; 250: FALRMKIKEV ; KKENGDKKIV ; PKKKKPLKLG ; PIKKKELKKL ; VLYLKNGADC ; 300: PCHQLDNLSH ; HFLIMGRKVK ; SQYLLTAIHK ; WDKKNKEFKT ; FMKKMKNHEC ; 308: PTFQSVFK
Sequence Length	308
String	O19116
Sub Unit	Interacts with WNT1, WNT2, WNT4 and WNT8 and FRZD6.

Uniprot	O19116
Gene Name	SFRP1
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:282068
Unigene	Bt.5226

Reference	1. "Identification and cloning of a secreted protein related to the cysteine-rich domain of frizzled: evidence for a role in endothelial cell growth control." Duplaa C., Jaspard B., Moreau C., D'Amore P.A. Circ. Res.84:1433-1445(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY tissue: Aortic endothelium.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809529	E1165b	96T	$900		Add to Cart

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