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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine RuvB-like 2

SKU : BHE13810041

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3289b
Categories	Elisa
Function	Plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. May also inhibit the transcriptional activity of ATF2.
Specificity	Natural and recombinant Bovine RuvB-like 2
Subcellular Location	Nucleus
Entryname	RUVB2_BOVIN
Platform	PF06068
Protein Name	RuvB-like 2
Sequence	50: MATVTATTKV ; PEIRDVTRIE ; RIGAHSHIRG ; LGLDDALEPR ; QASQGMVGQL ; 100: AARRAAGVVL ; EMIREGKIAG ; RAVLIAGQPG ; TGKTAIAMGM ; AQALGPDTPF ; 150: TAIAGSEIFS ; LEMSKTEALT ; QAFRRSIGVR ; IKEETEIIEG ; EVVEIQIDRP ; 200: ATGTGSKVGK ; LTLKTTEMET ; IYDLGTKMIE ; SLTKDKVQAG ; DVITIDKATG ; 250: KISKLGRSFT ; RARDYDAMGS ; QTKFVQCPDG ; ELQKRKEVVH ; TVSLHEIDVI ; 300: NSRTQGFLAL ; FSGDTGEIKS ; EVREQINAKV ; AEWREEGKAE ; IIPGVLFIDE ; 350: VHMLDIESFS ; FLNRALESDM ; APVLIMATNR ; GITRIRGTSY ; QSPHGIPIDL ; 400: LDRLLIVSTS ; PYSEKDKKQI ; LRIRCEEEDV ; EMSEDAYTVL ; TRIGLETSLR ; 450: YAIQLITAAS ; LVCRKRKGTE ; VQVDDIKRVY ; SLFLDESRST ; QYMKEYQDAF ; 463: LFNELKGETM ; DTS
Sequence Length	463
String	Q2TBU9
Sub Unit	Forms homohexameric rings (Probable). Can form a dodecamer with RUVBL1 made of two stacked hexameric rings; however, even though RUVBL1 and RUVBL2 are present in equimolar ratio, the oligomeric status of each hexamer is not known. Oligomerization may regulate binding to nucleic acids and conversely, binding to nucleic acids may affect the dodecameric assembly. Interacts with the transcriptional activation domain of MYC. Interacts With ATF2. Component of the RNA polymerase II holoenzyme complex. May also act to bridge the LEF1/TCF1-CTNNB1 complex and TBP. Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6. The NuA4 complex interacts with MYC and the adenovirus E1A protein. RUVBL2 interacts with EP400. Component of a NuA4-related complex which contains EP400, TRRAP/PAF400, SRCAP, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, actin, ACTL6A/BAF53A, VPS72 and YEATS4/GAS41. Interacts with NPAT. Component of the chromatin-remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80. Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, IN80C, KIAA1267, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with IGHMBP2.

Uniprot	Q2TBU9
Gene Name	RUVBL2
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:511048
Unigene	Bt.24670

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2005-11) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Crossbred X Angus. tissue: Liver.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810041	E3289b	96T	$900		Add to Cart

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