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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine RAF proto-oncogene serine/threonine-protein kinase

SKU : BHE13808248

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9583b
Alternative Names	Proto-oncogene c-RAF ; cRaf ; Raf-1
Categories	Elisa
Function	Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3/MST2.
Specificity	Natural and recombinant Bovine RAF proto-oncogene serine/threonine-protein kinase
Subcellular Location	Cytoplasm Cell membrane
Entryname	RAF1_BOVIN
Platform	PF00130
Protein Name	RAF proto-oncogene serine/threonine-protein kinase
Sequence	50: MEHIQGAWKT ; ISNGFGFKDT ; VFDGTSCISP ; TIVQQFGYQR ; RASDDGKLTD ; 100: PSKTSNTIRV ; FLPNKQRTVV ; NVRNGMSLHD ; CLMKALKVRG ; LQPECCAVFR ; 150: LLHEHKGKKA ; RLDWNTDAAS ; LIGEELQVDF ; LDHVPLTTHN ; FARKTFLKLA ; 200: FCDICQKFLL ; NGFRCQTCGY ; KFHEHCSTKV ; PTMCVDWSNI ; RQLLLFPNST ; 250: VGDGGVPALP ; SLTMRRMRES ; VSRIPPGSQH ; RYSTPHAFTF ; SASSPSSEGS ; 300: LSQRQRSTST ; PNVHMVSATL ; PVDSRMIEDA ; IRSHSESGSP ; SALSSSPNNL ; 350: SPTGWSQPKT ; PAPAQRERAP ; GSSTQEKNKI ; RPRGQRDSSY ; YWEIEASEVM ; 400: LSTRIGSGSF ; GTVYKGKWHG ; DVAVKILKVV ; DPTPEQFQAF ; RNEVAVLRKT ; 450: RHVNILLFMG ; YMTKDNLAIV ; TQWCEGSSLY ; KHLHVQETKF ; QMFQLIDIAR ; 500: QTAQGMDYLH ; AKNIIHRDMK ; SNNIFLHEGL ; TVKIGDFGLA ; TVKSRWSGSQ ; 550: QVEQPTGSIL ; WMAPEVIRMQ ; DNNPFSFQSD ; VYSYGIVLYE ; LMTGELPYSH ; 600: INNRDQIIFM ; VGRGYASPDL ; SKLYKNCPKA ; MKRLVADCVK ; KVKEERPLFP ; 648: QILSSIELLQ ; HSLPKINRSA ; SEPSLHRAAH ; TEDINACTLT ; TSPRLPVF
Sequence Length	648
String	A7E3S4
Sub Unit	Forms a multiprotein complex with Ras (M-Ras/MRAS), SHOC2 and protein phosphatase 1 (PPP1CA, PPP1CB and PPP1CC). Interacts with Ras proteins; the interaction is antagonized by RIN1. Weakly interacts with RIT1. Interacts with STK3/MST2; the interaction inhibits its pro-apoptotic activity. Interacts (when phosphorylated at Ser-259) with YWHAZ (unphosphorylated at 'Thr-232'). Interacts (via N-terminus) with RGS14 (via RBD domains); the interaction mediates the formation of a ternary complex with BRAF, a ternary complex inhibited by GNAI1.

Uniprot	A7E3S4
Gene Name	RAF1
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:521196
Unigene	Bt.4968

Reference	1. "Characterization of 954 bovine full-CDS cDNA sequences." Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L., Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L. BMC Genomics6:166-166(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1) 2. NIH - Mammalian Gene Collection (MGC) project Submitted (2007-07) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2) strain: Hereford. tissue: Heart ventricle.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808248	E9583b	96T	$900		Add to Cart

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