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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Proto-oncogene c-Fos

SKU : BHE13804383

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1291b
Alternative Names	Cellular oncogene fos
Categories	Elisa
Function	Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Specificity	Natural and recombinant Bovine Proto-oncogene c-Fos
Subcellular Location	Nucleus
Entryname	FOS_BOVIN
Platform	PF00170
Protein Name	Proto-oncogene c-Fos
Sequence	50: MMFSGFNADY ; EASSSRCSSA ; SPAGDSLSYY ; HSPADSFSSM ; GSPVNAQDYC ; 100: TDLAVSSANF ; IPTVTAISTS ; PDLQWLVQPT ; LVSSVAPSQT ; RAPHPYGVPT ; 150: PSAGAYSRAG ; VMKTMTGGRA ; QSIGRRGKVE ; QLSPEEEEKR ; RIRRERNKMA ; 200: AAKCRNRRRE ; LTDTLQAETD ; QLEDEKSALQ ; TEIANLLKEK ; EKLEFILAAH ; 250: RPACKIPDDL ; GFPEEMSVAS ; LDLSGGLPEA ; ATPESEEAFT ; LPLLNDPEPK ; 300: PSVEPVKSVG ; SMELKAEPFD ; DYMFPASSRP ; SGSETARSVP ; DMDLSGSFYA ; 350: ADWEPLHGGS ; LGMGPMATEL ; EPLCTPVVTC ; TPSCTTYTSS ; FVFTYPEADS ; 380: FPSCAAAHRK ; GSSSNEPSSD ; SLSSPTLLAL ;
Sequence Length	380
String	O77628
Sub Unit	Heterodimer; with JUN (By similarity). Component of the SMAD3/SMAD4/JUN/FOS complex required for syngernistic TGF-beta-mediated transcription at the AP1-binding site. Interacts with SMAD3; the interaction is weak even on TGF-beta activation. Interacts with MAFB. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with MAFB.

Uniprot	O77628
Gene Name	FOS
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:280795
Unigene	Bt.52605

Reference	1. "Characterization of c-Fos proto-oncogene in Korean native cattle (Hanwoo)." Yu S.L., Chung H.J., Jung K.C., Choi J.G., Na K.J., Lee J.H., Sang B.C. Submitted (2003-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Characterization of 954 bovine full-CDS cDNA sequences." Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L., Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L. BMC Genomics6:166-166(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 3. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Fetal skin. 4. "Stimulation of c-fos and c-jun mRNA in bovine luteal cells." Davis J.S., Fong H.W., Westfall S.W. Submitted (1998-06) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 165-290 tissue: Brain.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804383	E1291b	96T	$900		Add to Cart

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