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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Presenilin-2

SKU : BHE13808722

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1274b
Categories	Elisa
Function	Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins.
Specificity	Natural and recombinant Bovine Presenilin-2
Subcellular Location	Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein
Detection Range	31.2-2000pg/ml
Entryname	PSN2_BOVIN
Method Type	Sandwich
Platform	PF01080
Protein Name	Presenilin-2
Sensitivity	12.4pg/ml
Sequence	50: MLTFMASDSE ; EEVCDERTSL ; MSAESPTPRS ; CQDGRQGLED ; GESAAQWRSQ ; 100: ESEEDHEEED ; PDRYVCSGVP ; GRPPGLEEEL ; TLKYGAKHVI ; MLFVPVTLCM ; 150: IVVVATIKSV ; RFYTEKNGQL ; IYTPFSEDTP ; SVGQRLLNSV ; LNTLIMISVI ; 200: VTMTIFLVVL ; YKYRCYKFIH ; GWLIMSSLML ; LFLFTYIYLG ; EVLKTYNVAM ; 250: DYPTLFLTVW ; NFGAVGMVCI ; HWKGPLVLQQ ; AYLIMISALM ; ALVFIKYLPE ; 300: WSAWVILGAI ; SVYDLVAVLC ; PKGPLRMLVE ; TAQERNEPIF ; PALIYSSAMV ; 350: WTVGMAKLDP ; SSQGALQLPY ; DPEMEEDSYD ; SFGEPSYPDV ; FEPPLPGYPG ; 400: EELEEEEERG ; VKLGLGDFIF ; YSVLVGKAAA ; TGSGDWNTTL ; ACFVAILIGL ; 449: CLTLLLLAVF ; KKALPALPIS ; ITFGLIFYFS ; TDNLVRPFMD ; TLASHQLYI
Sequence Length	449
String	Q9XT96
Sub Unit	Homodimer. Component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PEN2. Such minimal complex is sufficient for secretase activity, although other components may exist. Interacts with DOCK3. Interacts with HERPUD1, FLNA and FLNB.

Uniprot	Q9XT96
Gene Name	PSEN2
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:282010
Unigene	Bt.41904

Reference	1. "Molecular cloning of bovine presenilin 2 gene." Sahara N., Shirasawa T., Mori H. Submitted (1997-12) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Brain. 2. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-01) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Heart ventricle.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808722	E1274b	96T	$900		Add to Cart

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