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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Mothers against decapentaplegic homolog 1

SKU : BHE13810391

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0647b
Alternative Names	SMAD family member 1 ; SMAD 1
Categories	Elisa
Function	Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).
Specificity	Natural and recombinant Bovine Mothers against decapentaplegic homolog 1
Subcellular Location	Cytoplasm Nucleus Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4. Co-localizes with LEMD3 at the nucleus inner membrane (By similarity). Forms a ternary complex with PSMB4 and OAZ1 before PSMB4 is incorporated into the 20S proteasome.
Detection Range	78-5000pg/mL
Entryname	SMAD1_BOVIN
Method Type	Sandwich
Platform	PF03165
Protein Name	Mothers against decapentaplegic homolog 1
Sensitivity	36pg/mL
Sequence	50: MNVTSLFSFT ; SPAVKRLLGW ; KQGDEEEKWA ; EKAVDALVKK ; LKKKKGAMEE ; 100: LEKALSCPGQ ; PSNCVTIPRS ; LDGRLQVSHR ; KGLPHVIYCR ; VWRWPDLQSH ; 150: HELKPLECCE ; FPFGSKQKEV ; CINPYHYKRV ; ESPVLPPVLV ; PRHSEYNPQH ; 200: SLLAQFRNLG ; QNEPHMPLNA ; TFPDSFQQPN ; SHPFPHSPNS ; SYPNSPGSSS ; 250: STYPHSPTSS ; DPGSPFQMPA ; DTPPPAYLPP ; EDPMTQDGSQ ; PMDTNMMAPS ; 300: LPSEINRGDV ; QAVAYEEPKH ; WCSIVYYELN ; NRVGEAFHAS ; STSVLVDGFT ; 350: DPSNNKNRFC ; LGLLSNVNRN ; STIENTRRHI ; GKGVHLYYVG ; GEVYAECLSD ; 400: SSIFVQSRNC ; NYHHGFHPTT ; VCKIPSGCSL ; KIFNNQEFAQ ; LLAQSVNHGF ; 450: ETVYELTKMC ; TIRMSFVKGW ; GAEYHRQDVT ; STPCWIEIHL ; HGPLQWLDKV ; 465: LTQMGSPHNP ; ISSVS
Sequence Length	465
String	Q1JQA2
Sub Unit	Interacts with HGS, NANOG and ZCCHC12 (By similarity). May form trimers with another SMAD1 and the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit, CREB-binding protein (CBP), p300, SMURF1, SMURF2 and HOXC8. Associates with ZNF423 or ZNF521 in response to BMP2 leading to activate transcription of BMP target genes. Interacts with SKOR1. Interacts (via MH2 domain) with LEMD3. Binding to LEMD3 results in at least a partial reduction of receptor-mediated phosphorylation.

Uniprot	Q1JQA2
Gene Name	SMAD1
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:540488
Unigene	Bt.37151

Reference	1. "Cloning and bioinformatic analysis of cDNA encoding cattle Smad1 gene." Zhang X., Xu S. Submitted (2006-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-05) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Ascending colon.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810391	E0647b	96T	$900		Add to Cart

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