ELISA Kit for Bovine Lymphotoxin-alpha

Mfr.No.	E0134b
Alternative Names	TNF-beta ; Tumor necrosis factor ligand superfamily member 1 ; TNFB ; TNFSF1
Categories	Elisa
Function	Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and cytotoxic for a wide range of tumor cells in vitro and in vivo.
Specificity	Natural and recombinant Bovine Lymphotoxin-alpha
Subcellular Location	Secreted Membrane The homotrimer is secreted (By similarity). The heterotrimer is membrane-associated.
Detection Range	0.156-10ng/mL
Entryname	TNFB_BOVIN
Method Type	Sandwich
Platform	PF00229
Protein Name	Lymphotoxin-alpha
Sensitivity	0.066ng/mL
Sequence	50: MTPPGRLYLL ; RVCSTPPLLL ; LGLLLALPLE ; AQGLRGIGLT ; PSAAQPAHQQ ; 100: LPTPFTRGTL ; KPAAHLVGDP ; STQDSLRWRA ; NTDRAFLRHG ; FSLSNNSLLV ; 150: PTSGLYFVYS ; QVVFSGRGCF ; PRATPTPLYL ; AHEVQLFSPQ ; YPFHVPLLSA ; 200: QKSVCPGPQG ; PWVRSVYQGA ; VFLLTRGDQL ; STHTDGISHL ; LLSPSSVFFG ; 204: AFAL
Sequence Length	204
String	Q06600
Sub Unit	Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits.

Reference	1. "Cloning and characterization of the tandemly arranged bovine lymphotoxin and tumour necrosis factor-alpha genes." Cludts I., Cleuter Y., Kettmann R., Burny A., Droogmans L. Cytokine5:336-341(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] 2. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Uterus.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811344	E0134b	96T	$900		Add to Cart