May play an integral structural role in elastic-fiber architectural organization and/or assembly. May be involved in the assembly, secretion and targeting of TGF- beta to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGF-beta. May have a structural role in the extra cellular matrix (ECM).
Specificity
Natural and recombinant Bovine Latent-transforming growth factor beta-binding protein 2
Subcellular Location
Secreted extracellular space extracellular matrix Localized in nuchal ligament and aorta to the fibrillin-containing, microfibrillar component of elastic fibers.