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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Interleukin-12 subunit beta

SKU : BHE13804878

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0058b
Alternative Names	Cytotoxic lymphocyte maturation factor 40 kDa subunit ; CLMF p40 ; IL-12 subunit p40
Categories	Elisa
Function	Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Specificity	Natural and recombinant Bovine Interleukin-12 subunit beta
Subcellular Location	Secreted
Detection Range	78-5000pg/mL
Entryname	IL12B_BOVIN
Method Type	Sandwich
Platform	PF10420
Protein Name	Interleukin-12 subunit beta
Sensitivity	33pg/mL
Sequence	50: MHPQQLVVSW ; FSLVLLASPI ; VAMWELEKNV ; YVVELDWYPD ; APGETVVLTC ; 100: DTPEEDGITW ; TSDQSSEVLG ; SGKTLTIQVK ; EFGDAGQYTC ; HKGGEALSRS ; 150: LLLLHKKEDG ; IWSTDILKDQ ; KEPKAKSFLK ; CEAKDYSGHF ; TCWWLTAIST ; 200: DLKFSVKSSR ; GSSDPRGVTC ; GAALLSAEKV ; SLEHREYNKY ; TVECQEGSAC ; 250: PAAEESLLIE ; VVVEAVHKLK ; YENYTSSFFI ; RDIIKPDPPK ; NLQLRPLKNS ; 300: RQVEVSWEYP ; DTWSTPHSYF ; SLTFCVQVQG ; KNKREKKLFM ; DQTSAKVTCH ; 327: KDANVRVQAR ; DRYYSSFWSE ; WASVSCS
Sequence Length	327
String	P46282
Sub Unit	Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12. Heterodimer with IL23A; disulfide-linked. The heterodimer is known as interleukin IL-23. Also secreted as a monomer.

Uniprot	P46282
Gene Name	IL12B
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:281857
Unigene	Bt.523

Reference	1. "Enzymatic amplification and molecular cloning of cDNA encoding the small and large subunits of bovine interleukin 12." Zarlenga D.S., Canals A., Aschenbrenner R.A., Gasbarre L.C. Biochim. Biophys. Acta1270:215-217(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Holstein. tissue: Lymphoid tissue. 2. "U.S. veterinary immune reagent network: expressed bovine gene sequences." U.S. Veterinary Immune Reagent Network, Hudgens T., Tompkins D., Baldwin C.L. Submitted (2007-11) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Belted Galloway. tissue: Peripheral blood.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804878	E0058b	96T	$900		Add to Cart

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