CD49 antigen-like family member B ; Collagen receptor ; Platelet membrane glycoprotein Ia ; GPIa ; VLA-2 subunit alpha ; CD49b
Categories
Elisa
Function
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.