ELISA Kit for Bovine Inducible T-cell costimulator

Mfr.No.	E15375b
Alternative Names	CD278
Categories	Elisa
Function	Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
Specificity	Natural and recombinant Bovine Inducible T-cell costimulator
Subcellular Location	Membrane Single-pass type I membrane protein
Entryname	ICOS_BOVIN
Protein Name	Inducible T-cell costimulator
Sequence	50: MKSDLRYFFL ; FCIQVEILAG ; EFNDSAASEM ; FIFHNGGVQI ; LCKYPDTVRQ ; 100: FKMQLLKGDN ; VLCDLTKTKE ; NEDTVSIRNL ; NVCKFQLSNN ; SVSFFLYNLD ; 150: SSYASYYICK ; LSIFDPPPFQ ; VDILSREYLN ; IYESELCCQL ; KFWLPIGCAA ; 200: FVTVCVFGCV ; LMYWLTKKKY ; PTSVHDPNSE ; YMFMAAVNTA ; KKPAPTDVTR ; 209: NLELPGTQA
Sequence Length	209
String	Q58DF9
Sub Unit	Homodimer; disulfide-linked.

Reference	1. "Characterization of 954 bovine full-CDS cDNA sequences." Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L., Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L. BMC Genomics6:166-166(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805773	E15375b	96T	$900		Add to Cart