One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Specificity
Natural and recombinant Bovine Gap junction alpha-1 protein
Subcellular Location
Cell membrane Multi-pass membrane protein Cell junction gap junction
A connexon is composed of a hexamer of connexins. Interacts with SGSM3. Interacts with KIAA1432/CIP150. Interacts with CNST. Interacts (via C-terminus) with TJP1. Interacts (via C-terminus) with SRC (via SH3 domain).