JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine E3 ubiquitin-protein ligase HACE1

SKU : BHE13805492

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E4918b
Alternative Names	HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1 ; HECT-type E3 ubiquitin transferase HACE1
Categories	Elisa
Function	E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.
Specificity	Natural and recombinant Bovine E3 ubiquitin-protein ligase HACE1
Subcellular Location	Golgi apparatus Golgi stack membrane Cytoplasm Endoplasmic reticulum A significant portion localizes to the endoplasmic reticulum. Targeted to Golgi membrane via its interaction with Rab proteins.
Entryname	HACE1_BOVIN
Platform	PF12796
Protein Name	E3 ubiquitin-protein ligase HACE1
Sequence	50: MERAMEQLNR ; LTRSLRRART ; VELPDDNETA ; VYTLMPMVMA ; DQHRSVSELL ; 100: SNSKFDVNYA ; FGRVKRSLLH ; IAANCGSVEC ; LVLLLKKGAN ; PNYQDISGCT ; 150: PLHLAARNGQ ; KKCMSKLLEY ; SADVNICNNE ; GLTAIHWLAV ; NGRTELLHDL ; 200: VQHVSDVDVE ; DAMGQTALHV ; ACQNGHKTTV ; QCLLDSGADI ; NRPNVSGATP ; 250: LYFACSHGQR ; DTAQILLLRG ; AKYLSDKNGV ; TPLDLCVQGG ; YGETCEVLIQ ; 300: YHPRLFQTII ; QMTQNEDLRE ; NMLRQVLEHL ; SQQSESQYLK ; ILTSLAEVAT ; 350: TNGHKLLSIS ; SNYDAQMKSL ; LRIVRIFCHV ; FRIGPSSPSN ; GIDMGYNGNK ; 400: TPRSQVFKPL ; ELLWHSLDEW ; LVLIATELMK ; NKKDSTDITS ; ILLKQKGQDQ ; 450: DGTSIPPFEP ; PGPGSYENLS ; TGTGESKPDV ; LGGKQEASAD ; CQDVISMTAN ; 500: RLSAVIQAFY ; MCCSCQMPPG ; MTSPRFIEFV ; CKHDEVLKCF ; VNRNPKIIFD ; 550: HFHFLLECPE ; LMSRFMHIIK ; AQPFKDRCEW ; FYEHLHSGQP ; DSDMVHRPVN ; 600: ENDILLVHRD ; SIFRSSCEVV ; SKANCAKLKQ ; GIAVRFHGEE ; GMGQGVVREW ; 650: FDILSNEIVN ; PDYALFTQSA ; DGTTFQPNSN ; SSVNPDHLNY ; FRFAGQILGL ; 700: ALNHRQLVNI ; YFTRSFYKHI ; LGIPVNYQDV ; ASIDPEYAKN ; LQWILDNDIS ; 750: DLGLELTFSV ; ETDVFGAMEE ; VPLKPGGGSI ; LVTQNNKAEY ; VQLVTELRMT ; 800: RAIQPQINAF ; LQGFHMFIPP ; SLIQLFDEYE ; LELLLSGMPE ; IDVSDWIKNT ; 850: EYTSGYERED ; PVIQWFWEVV ; EDITPEERVL ; LLQFVTGSSR ; VPHGGFANIM ; 900: GGSGLQNFTI ; AAVPYTPNLL ; PTSSTCINML ; KLPEYPSKEI ; LKDRLLVALH ; 909: CGSYGYTMA
Sequence Length	909
Sub Unit	Interacts with RARB. Interacts with RAB1 (RAB1A, RAB1B or RAB1C), RAB4 (RAB4A or RAB4B) and RAB11 (RAB11A or RAB11B); in a GTP-dependent manner. Interacts with RAC1; in a GTP-dependent manner. Interacts with the 26S proteasomal complex through the 20S core proteasomal subunit.

Uniprot	F1N6G5
Gene Name	HACE1
Immunogen Species	Bos Taurus (Cattle)
Kegg	bta:527565
Unigene	Bt.30832

Reference	1. "A whole-genome assembly of the domestic cow, Bos taurus." Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L. Genome Biol.10:R42.01-R42.10(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] strain: Hereford.

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13805492	E4918b	96T	$900		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.