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Home / Assay Kits / ELISA Kits

ELISA Kit for Bovine Cyclin-dependent kinase 12

SKU : BHE13801646

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E6889b
Alternative Names	Cell division protein kinase 12
Categories	Elisa
Function	Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogn inhibitors.
Specificity	Natural and recombinant Bovine Cyclin-dependent kinase 12
Subcellular Location	Nucleus Nucleus speckle Colocalized with nuclear speckles throughout interphase.
Detection Range	78-5000pg/mL
Entryname	CDK12_BOVIN
Method Type	Sandwich
Platform	PF00069
Protein Name	Cyclin-dependent kinase 12
Sensitivity	34 pg/mL
Sequence	50: MPNPERHGGK ; KDGSGGASGT ; LQPSSGGGSS ; NSRERHRLGS ; KHKRHKSKHS ; 100: KDMGLVTPEA ; APLGTVIKPL ; VEYDDISSDS ; DTFSDDLAFK ; VDRRENDERR ; 150: GTDRSDRLHK ; HRHHQHRRTR ; DLLKTKQTEK ; EKNLEASSKS ; GSTKDRISGS ; 200: SKRSNEENDD ; HGKAQISKSS ; NKESRSSKLH ; KEKTRKEREL ; KSGHKDRSKS ; 250: HRKRETPKSY ; KTVDSPKRRS ; RSPHRKWSDS ; PKQDDSPSGA ; SYGQDYDLSP ; 300: PRSHTSSNYD ; SYKKSPGSTS ; RRQSISPPYK ; EPSAYQSSTR ; SPSPYSRRQR ; 350: SVSPYSRRRS ; SSYERSGSYS ; GRSPSPYGRR ; RSSSPFLSKR ; SLSRSPLPSR ; 400: KSMKSRSRSP ; AYSRHSSSHS ; KKKRSGSRSR ; HSSISPVRLP ; LNSSLGAELS ; 450: RKKKERAAAA ; AAAKMDGKES ; KGSPIFLPKK ; ENSSVEAKDS ; GLEPKKLPRG ; 500: VKLEKSAPDT ; ELVNVTHLNT ; EVKNSLDTGK ; VKLDENSEKH ; PVLKDTKVQG ; 550: TKDSKPVALK ; EEIVTPKETE ; TSEKETLPPL ; PTVTSPPPLP ; TTTPPPQTPP ; 600: LPPLPPLPAI ; PQQPPLPPPQ ; PTFSQVLSSS ; TSTLPPSVHP ; RTSTLSSQAN ; 650: SQPSVQVSVK ; TQVSVTAAIP ; HLKTSTLPPL ; PLPPLLLGDD ; DMDSPKETLP ; 700: SKPVKKEKEQ ; RPRHLLTDLP ; LPPELPGGDP ; SPPDSPEPKA ; ITPPQQPYKK ; 750: RPKICCPRYG ; ERRQTESDWG ; KRCVDKFDII ; GIIGEGTYGQ ; VYKAKDKDTG ; 800: ELVALKKVRL ; DNEKEGFPIT ; AIREIKILRQ ; LIHRSVVNMK ; EIVTDKQDAL ; 850: DFKKDKGAFY ; LVFEYMDHDL ; MGLLESGLVH ; FSEDHIKSFM ; KQLMEGLDYC ; 900: HKKNFLHRDI ; KCSNILLNNS ; GQIKLADFGL ; ARLYNSEESR ; PYTNKVITLW ; 950: YRPPELLLGE ; ERYTPAIDVW ; SCGCILGELF ; TKKPIFQANL ; ELAQLELISR ; 1000: LCGSPCPAVW ; PDVIKLPYFN ; TMKPKKQYRR ; RLREEFSFFF ; LPWGALDLLD ; 1050: HMLTLDPSKR ; CTAEQTLQSD ; FLKDVELSKM ; DPPDLPHWQD ; CHELWSKKRR ; 1100: RQRQSGVLVE ; EPPPPKASRK ; ETISGTSAEP ; VKNSSPAPPQ ; PAPGKVEPGA ; 1150: GDAIGLGDIT ; QQLNQSELAV ; LLNLLQSQTD ; LSIPQMAQLL ; NIHSNPEMQQ ; 1200: QLEALNQSIS ; ALTAATSQQQ ; DSEPTAPEES ; LKEIAPAPAV ; QPSAEQTTPE ; 1250: ASSTPADMQN ; MLAVLLSQLM ; KTQEPAGNLE ; ENNSDKNSGP ; QGPRRTPTMP ; 1264: QEEAAGKQTG ; HESH
Sequence Length	1264
Sub Unit	Interacts with CCNL1 and CCNL2.

Uniprot	E1BB50
Gene Name	CDK12
Immunogen Species	Bos Taurus (Cattle)
Unigene	Bt.67418

Reference	1. "The genome sequence of taurine cattle: a window to ruminant biology and evolution." The bovine genome sequencing and analysis consortium Science324:522-528(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801646	E6889b	96T	$900		Add to Cart

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