ELISA Kit for Bovine Breast cancer metastasis-suppressor 1 homolog

Mfr.No.	E9631b
Categories	Elisa
Function	Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis.
Specificity	Natural and recombinant Bovine Breast cancer metastasis-suppressor 1 homolog
Subcellular Location	Nucleus Cytoplasm Predominantly nuclear.
Entryname	BRMS1_BOVIN
Platform	PF08598
Protein Name	Breast cancer metastasis-suppressor 1 homolog
Sequence	50: MPVQPPSKDT ; EEMEAEGDSA ; AEMNGEEEES ; EEERSGSQTE ; SEEESSEMDE ; 100: EDCERRRSEC ; VSEMMDLEKQ ; FSELKEKLFR ; ERLSQLRVRL ; EEVGAERAPE ; 150: YTEPLGGLQR ; SLKIRIQVAG ; IYKGFCLDVI ; RNKYECELQG ; AKQHLESEKL ; 200: LLYDTLQGEL ; QERIQRLEED ; RQSLDISSEW ; WDDKLHARGS ; SRTWDSLPPN ; 246: KRKKAPLVSG ; PYIVYMLQEI ; DILEDWTAIK ; KARAAVSPQK ; RKSDGP
Sequence Length	246
Sub Unit	Interacts with SNX6, HDAC1 and RELA. Interacts with ARID4A. Identified in mSin3A corepressor complexes together with SIN3A, SIN3B, RBBP4, RBBP7, SAP30, SUDS3, ARID4A, HDAC1 and HDAC2.

Reference	1. NIH - Mammalian Gene Collection (MGC) project Submitted (2006-05) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] strain: Hereford. tissue: Ascending colon.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801674	E9631b	96T	$900		Add to Cart