Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu- ; -Ala-393' site.
Specificity
Natural and recombinant Bovine A disintegrin and metalloproteinase with thrombospondin motifs 4
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 213-239; 610-615 AND 626-637