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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Microtubule-associated protein RP/EB family member 1

SKU : BHE13806299

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2190r
Alternative Names	APC-binding protein EB1 ; End-binding protein 1 ; EB1
Categories	Elisa
Function	May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
Specificity	Natural and recombinant Rat Microtubule-associated protein RP/EB family member 1
Subcellular Location	Cytoplasm Cytoplasm cytoskeleton Cytoplasm cytoskeleton centrosome Associated with the microtubule network at the growing distal tip of microtubules. Also enriched at the centrosome.
Detection Range	0.156-10ng/mL
Entryname	MARE1_RAT
Method Type	Sandwich
Platform	PF00307
Protein Name	Microtubule-associated protein RP/EB family member 1
Sensitivity	0.091ng/mL
Sequence	50: MAVNVYSTSV ; TSDNLSRHDM ; LAWINESLQL ; NLTKIEQLCS ; GAAYCQFMDM ; 100: LFPGSIALKK ; VKFQAKLEHE ; YIQNFKILQA ; GFKRMGVDKI ; IPVDKLVKGK ; 150: FQDNFEFVQW ; FKKFFDANYD ; GKEYDPVAAR ; QGQETAVAPS ; LVAPALSKPK ; 200: KPLGSGSAAP ; QRPIATQRTT ; AAPKAGPGMV ; RKNPGMGNGD ; DEAAELMQQV ; 250: KVLKLTVEDL ; EKERDFYFGK ; LRNIELICQE ; NEGENDPVLQ ; RIVDILYATD ; 268: EGFVIPDEGG ; PQEEQEEY
Sequence Length	268
String	Q66HR2
Sub Unit	Homodimer. Interacts with DCTN1, DCTN2, DIAPH1, DIAPH2, TERF1 and dynein intermediate chain. Interacts with APC (via C-terminal domain), CLASP2, DST, KIF2C and STIM1; probably required for their targeting to the growing microtubule plus ends. Interacts with MTUS2; interaction is direct and probably targets MTUS2 to microtubules. Interacts with APC2. Interacts with CLASP1 (By similarity). According to PubMed:19553473, MAPRE1 does not interact with CDK5RAP2 (By similarity). Interacts with MACF1.

Uniprot	Q66HR2
Gene Name	Mapre1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:114764
Unigene	Rn.7652

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Heart. 2. Bienvenut W.V., von Kriegsheim A.F., Kolch W. Submitted (2006-08) to the UniProtKB [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-17; 67-98; 113-150; 182-201 AND 205-214;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY tissue: Pheochromocytoma. 3. "Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics." Fong K.W., Hau S.Y., Kho Y.S., Jia Y., He L., Qi R.Z. Mol. Biol. Cell20:3660-3670(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806299	E2190r	96T	$796		Add to Cart

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