Elastin microfibril interface-located protein 1 ; Elastin microfibril interfacer 1
Categories
Elisa
Function
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity (By similarity). May have a function in placenta formation and initial organogenesis and a later role in interstitial connective tissue.
Specificity
Natural and recombinant Mouse EMILIN-1
Subcellular Location
Secreted extracellular space extracellular matrix Found mainly at the interface between amorphous elastin and microfibrils.
Homotrimer associated through a moderately stable interaction of the C-terminal globular C1q domains, allowing the nucleation of the triple helix and then a further quateary assembly to higher order polymers via intermolecular disulfide bonds. Interacts with EMILIN2.